제품 소개제약 원료

Crizotinib 익지않는 분말 항 종양성 Multitarget 프로테아제 억제물 877399-52-5

Crizotinib 익지않는 분말 항 종양성 Multitarget 프로테아제 억제물 877399-52-5

    • Crizotinib Raw Powder Antineoplastic Multitarget Protease Inhibitors 877399-52-5
    • Crizotinib Raw Powder Antineoplastic Multitarget Protease Inhibitors 877399-52-5
  • Crizotinib Raw Powder Antineoplastic Multitarget Protease Inhibitors 877399-52-5

    제품 상세 정보:

    원래 장소: 중국
    브랜드 이름: FuLu
    인증: ISO9001
    모델 번호: 1421373-65-0

    결제 및 배송 조건:

    최소 주문 수량: 협상 가능한
    가격: Negotiable
    포장 세부 사항: 1kg 보장되는 관례 통행을 위한 메마른 알루미늄 호일 부대 또는 신중하고 단단한 안전한 패킹
    배달 시간: 지불 후에 24h 안에
    지불 조건: 서부 동맹, MoneyGram, T/T의 조금 동전
    공급 능력: 대량 주식
    지금 연락
    상세 제품 설명
    제품 이름: Crizotinib 를: 의약품 중간체
    용법: 항 종양성 유형: 제약 원료
    백색 분말: 백색 분말 CAS: 1421373-65-0
    하이 라이트:

    active pharmaceutical ingredients

    ,

    raw material medicine

    Crizotinib Raw Powder Antineoplastic Multitarget Protease Inhibitors

     

    Basic infor

     

     

    Product name

    Crizotinib

    CAS

    877399-52-5

    MF

    C21H22Cl2FN5O

    MW

    450.343

    Purity

    99% min

    Appearance

    White Crystalline Powder

    MOQ

    10 grams

    Storage

    Store in a cool, dry place

    Deliver time

    About 5 days

    Deliver methods

    By express (door to door)

     

     

    What is Crizotinib

     


    Crizotinib (trade name Xalkori,) is an anti-cancer drug acting as an ALK (anaplastic lymphoma kinase) and ROS1 (c-ros oncogene 1) inhibitor, approved for treatment of some non-small cell lung carcinoma (NSCLC) in the US and some other countries, and undergoing clinical trials testing its safety and efficacy inanaplastic large cell lymphoma, neuroblastoma, and other advanced solid tumors in both adults and children.

     

     

    How does Crizotinib works
     


    Crizotinib has an aminopyridine structure, and functions as a protein kinase inhibitor by competitive binding within the ATP-binding pocket of target kinases. About 4% of patients with non-small cell lung carcinoma have a chromosomal rearrangement that generates a fusion genebetween EML4 ('echinoderm microtubule-associated protein-like 4') andALK ('anaplastic lymphoma kinase'), which results in constitutivekinase activity that contributes to carcinogenesis and seems to drive the malignant phenotype. The kinase activity of the fusion protein is inhibited by crizotinib. Patients with this gene fusion are typically younger non-smokers who do not have mutations in either theepidermal growth factor receptor gene (EGFR) or in the K-Ras gene.The number of new cases of ALK-fusion NSLC is about 9,000 per year in the U.S. and about 45,000 worldwide.

     

     

    COA

     

     

    Test Items

    Specification

    Results

    Description

    White to off white crystalline powder

    Comply

    Melting point

    166-170ºC

    167.3-168.1ºC

    Identification

    Positive reaction

    Positive reaction

    Related substances

    <1.0%

    0.16%

    Loss on drying

    <0.5%

    0.06%

    Residue on ignition

    <0.1%

    0.02%

    Chloride

    <0.014%

    <0.014

    Heavy Metals

    <20ppm

    <20ppm

    Clarity of solution

    Conform to standard

    Complies

    Microbial Limit

    <20ppm

    <20ppm

    Assay

    >99.0%

    99.12%

     

     

    High quality with competitive price

     

     

    1)Tell the package update ASAP , and will try best solve when customer encountered various problems.

    2)we will teach you recipes and instructions for all kind of steroid to turn powder into liquid , and liquid become sterile ones.


    We have clients throughout the world

     

     

    1)Professional service and rich experience make customers feel comfortable and trust us.

    2)Adequate stock(such as Anti Estrogen Steroids) and fast delivery meet their demand.

    3)Market feedback and products feedback will be appreciated, meeting customers's requirement is our responsibility.

    4) High quality and competitive price gain the trust and praise from the customers around the world.


    Fast and safe delivery

     

     

    1)Parcel can be sent out in 24 hours after comfirming payment.

    2) Various transportation methods for your choice , such as EMS , FedEx , TNT , DHL , USP.

    3) We have our own agent who can help us ship our products fastly and safely , and we have enough stock in there for transferring.

    4)We have special way could ship 10g to sveral kg products a time. We offer melting powder into liquid service. And ship the liquid in special package ways.

    5)Offer the latest tracking number for you to check.

     

     


    Flexible Payment term

     


    We accept every payment term , such as T/T , Bitcoin , Moneygram , .

    High quality with competitive price
    We are manufacturer and can provide high quality products with competitive price , offering free samples totest , a few shipping fee only.

     

     

    Crizotinib 익지않는 분말 항 종양성 Multitarget 프로테아제 억제물 877399-52-5

     

     

     

    연락처 세부 사항
    SuZhou FuLu Biotech Co.,Ltd

    담당자: Jessie

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